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Quetiapine - AstraZeneca

Drug Profile

Quetiapine - AstraZeneca

Alternative Names: FK 949; FK949E; ICI 204636; Quetiapine extended release; Quetiapine fumarate; Quetiapine prolonged release; Seroquel; Seroquel XL; Seroquel XR

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator AstraZeneca
  • Developer Astellas Pharma; AstraZeneca; Hutchison MediPharma; Luye Pharma Group
  • Class Analgesics; Antidepressants; Antipsychotics; Behavioural disorder therapies; Dibenzothiazepines; Mood stabilisers; Piperazines; Small molecules
  • Mechanism of Action Adrenergic uptake inhibitors; Alpha 2 adrenergic receptor antagonists; Dopamine D2 receptor antagonists; Serotonin 1A receptor agonists; Serotonin 2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bipolar depression; Bipolar disorders; Major depressive disorder; Manic episodes; Schizophrenia
  • Phase III Borderline personality disorders
  • Preregistration Submission Withdrawal Generalised anxiety disorder
  • No development reported Delirium; Irritable bowel syndrome
  • Discontinued Alcoholism; Behavioural disorders; Psychotic disorders

Most Recent Events

  • 22 Jul 2018 Launched for Bipolar depression in China (PO)
  • 22 Jul 2018 Registered for Bipolar depression in China (PO)
  • 22 Jul 2018 Chinese medical authorities approves sustained-release quetiapine fumarate XR for treatment of depression arising from bipolar disorder in China
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