Duloxetine - Eli Lilly

Drug Profile

Duloxetine - Eli Lilly

Alternative Names: Ariclaim; Cymbalta; LY-227942; LY-248686; Xeristar; Yentreve

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Eli Lilly
  • Developer Eli Lilly; Shionogi
  • Class Antidepressants; Naphthalenes; Non-opioid analgesics; Propanolamines; Small molecules; Thiophenes
  • Mechanism of Action Adrenergic uptake inhibitors; Serotonin plasma membrane transport protein inhibitors; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Back pain; Depressive disorders; Diabetic neuropathies; Fibromyalgia; Generalised anxiety disorder; Major depressive disorder; Musculoskeletal pain; Neuropathic pain; Stress incontinence
  • Phase II/III Chronic fatigue syndrome

Most Recent Events

  • 05 Feb 2018 Eli Lilly initiates enrolment in a phase III trial for Major depressive disorder in Japan (JapicCTI-183853)
  • 29 Jan 2018 Eli Lilly and Shionogi initiates enrolment in a phase III trial for Major depressive disorder (In adolescents, In children) in Japan (PO) (NCT03395353)
  • 10 Jan 2018 Eli Lilly plans a phase III trial for Major depressive disorder in January 2018 , (NCT03395353)
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