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Anakinra - Swedish Orphan Biovitrum

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Drug Profile

Anakinra - Swedish Orphan Biovitrum

Alternative Names: 143090-92-0; Antril; Kinaret; Kineret; Recombinant human interleukin-1 receptor antagonist; rhIL-1ra; rIL-1ra; rIL1RN

Latest Information Update: 09 Oct 2025

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At a glance

  • Originator Amgen
  • Developer Amgen; CHRU de Tours; Swedish Orphan Biovitrum
  • Class Anti-infectives; Anti-inflammatories; Antibacterials; Antigouts; Antineoplastics; Antirheumatics; Recombinant proteins
  • Mechanism of Action Interleukin 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cryopyrin-associated periodic syndromes; Immunological disorders; Juvenile rheumatoid arthritis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cryopyrin-associated periodic syndromes; Rheumatoid arthritis
  • Registered Adult-onset Still's disease; Autoimmune disorders; COVID-19 pneumonia; Familial Mediterranean fever; Juvenile rheumatoid arthritis
  • Phase III COVID 2019 infections
  • Phase II Gout; Non-Hodgkin's lymphoma
  • Discontinued Ankylosing spondylitis; Graft-versus-host disease; Osteoarthritis; Pneumococcal infections; Septic shock

Most Recent Events

  • 11 Apr 2025 Pharmacodynamics data from the phase III SAVE-MORE trial in COVID-2019 pneumonia presented at the 35th Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID-2025)
  • 31 Dec 2023 Registered for Cryopyrin-associated periodic syndromes in China (SC) prior to December 2023
  • 31 Dec 2023 Registered for Familial Mediterranean fever in China (SC) prior to December 2023

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