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Drug Profile


Alternative Names: A-007

Latest Information Update: 20 Jul 2015

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At a glance

  • Originator Barbara Ann Karmanos Cancer Institute; Dekk-Tec
  • Developer Kirax Corporation
  • Class Antineoplastics; Hydrazones; Small molecules
  • Mechanism of Action Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Anal intraepithelial neoplasia; Breast cancer; Cervical cancer; Cervical intraepithelial neoplasia; Kaposi's sarcoma; Lymphoma; Malignant melanoma

Most Recent Events

  • 03 Jul 2007 Data presented at the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2007) added to the adverse events section
  • 18 Jan 2007 Tigris Pharmaceuticals completes enrolment in the phase I/II trial for Anal intraepithelial neoplasia in USA
  • 18 Jan 2007 Tigris Pharmaceuticals completes enrolment in two registrational clinical trials for Cervical intraepithelial neoplasia in Mexico
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