Alemtuzumab - Bayer/Sanofi

Drug Profile

Alemtuzumab - Bayer/Sanofi

Alternative Names: Anti-CD52 monoclonal antibody; Campath; Campath-1H; LDP-03; Lemtrada; MabCampath; MabKampat; Remniq

Latest Information Update: 03 Aug 2018

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At a glance

  • Originator University of Cambridge
  • Developer Bayer HealthCare Pharmaceuticals Inc.; Dana-Farber Cancer Institute; German CLL Study Group; Ohio State University Comprehensive Cancer Center; Sanofi; Sanofi Oncology; University of Cologne
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action CD52 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia; Multiple sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Chronic lymphocytic leukaemia; Multiple sclerosis
  • Phase II T cell prolymphocytic leukaemia
  • Phase I Lymphoma
  • No development reported Diffuse large B cell lymphoma; Graft-versus-host disease; T cell lymphoma
  • Discontinued Rheumatoid arthritis

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 23 Apr 2018 Updated efficacy and safety data from the phase III CARE-MS extension trial in Multiple Sclerosis released by Genzyme
  • 19 Apr 2018 Updated efficacy data from the phase III CARE-MS extension trial in Multiple sclerosis released by Genzyme
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