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Tezacitabine - Edison Oncology

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Drug Profile

Tezacitabine - Edison Oncology

Alternative Names: EO-4426; FMdc; KW 2331; MDL 101731

Latest Information Update: 24 Feb 2026

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At a glance

  • Originator Aventis
  • Developer Edison Oncology Holding Corporation
  • Class Antineoplastics; Nucleosides; Small molecules
  • Mechanism of Action DNA polymerase I inhibitors; Ribonucleoside triphosphate reductase inhibitors; Ribonucleotide reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies; Solid tumours
  • Discontinued Acute myeloid leukaemia; Colorectal cancer; Non-small cell lung cancer; Oesophageal cancer; Viral infections

Most Recent Events

  • 24 Feb 2026 Edison Oncology plans a phase I/II trial for Solid tumours and Haematological malignances (PO) in first half of 2026 (Edison Oncology pipeline, December 2025)
  • 22 Oct 2025 Preclinical trials in Haematological malignancies in USA (PO)
  • 22 Oct 2025 Preclinical trials in Solid tumours in USA (PO)

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