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Edaravone - Mitsubishi Tanabe Pharma

Drug Profile

Edaravone - Mitsubishi Tanabe Pharma

Alternative Names: 1-phenyl-3-methyl-5-pyrazolone; Edarabone; MCI-186; MT 1186; Norphenazone; Phenylmethylpyrazolone; Radicava; Radicut; Radicut Bag

Latest Information Update: 11 Dec 2018

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At a glance

  • Originator Mitsubishi Pharma Corporation
  • Developer Mitsubishi Pharma Corporation; Mitsubishi Tanabe Pharma America; Mitsubishi Tanabe Pharma Corporation
  • Class Anti-ischaemics; Antihaemorrhagics; Antiparkinsonians; Hepatoprotectants; Neuroprotectants; Pyrazolones; Small molecules
  • Mechanism of Action Antioxidants; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Amyotrophic lateral sclerosis; Cerebral infarction
  • Phase II Stroke
  • Phase I Liver disorders
  • Discontinued Myocardial ischaemia; Parkinson's disease; Reperfusion injury; Subarachnoid haemorrhage

Most Recent Events

  • 15 Nov 2018 Pharmacokinetics data from a phase I trial in Amyotrophic lateral sclerosis released by Mitsubishi Tanabe Pharma
  • 06 Nov 2018 Phase-I clinical trials in Liver disorders in Hungary, Slovakia (IV) (NCT03664544)
  • 03 Oct 2018 Registered for Amyotrophic lateral sclerosis in Canada (IV)
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