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Drug Profile


Alternative Names: Atorvastatin calcium; Cardyl; CI 981; Lipitor; Prevencor; Sortis; Tahor; Xarator 10; YM 548; Zarator

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Parke-Davis
  • Developer Astellas Pharma; Laboratorios Phoenix; Pfizer; University of Rochester
  • Class Amides; Antihyperlipidaemics; Fatty acids; Fluorobenzenes; Heptanoic acids; Pyrroles; Small molecules
  • Mechanism of Action HMG-CoA reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Cardiovascular disorders; Heart failure; Hypercholesterolaemia; Hyperlipoproteinaemia type IIa; Hyperlipoproteinaemia type III; Hypertriglyceridaemia; Low HDL cholesterol
  • Phase III Veno-occlusive disorders
  • Phase I/II Metabolic syndrome
  • Discontinued Alzheimer's disease; Neurological disorders

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 01 Jan 2017 Pfizer and Boca Raton Regional Hospital completes a phase III trial in Veno-occlusive disorders in USA and Canada (NCT01528709)
  • 09 Oct 2015 No recent reports on development identified - Phase-II/III for Hyperlipoproteinaemia type IIa (In adolescents, In children) in Switzerland (PO)
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