Ibandronic acid - Roche
Alternative Names: BM 210955; Bondronat; Boniva; Bonviva; CT-064; Ibandronate; Ibandronate sodium hydrate; Methylpentylaminopropylidene; R 484; RG484; RO 2005450; Ro200-5450; Ro200-5450iv; Ro200-5450po; RPR 102289ALatest Information Update: 05 Nov 2023
At a glance
- Originator Roche
- Developer Chugai Pharmaceutical; Roche; Taisho Pharmaceutical
- Class Antihypercalcaemics; Bisphosphonates; Calcium regulators; Osteoporosis therapies; Small molecules
- Mechanism of Action Bone resorption factor inhibitors; Dimethylallyltranstransferase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Cancer metastases; Malignant hypercalcaemia; Osteoporosis; Postmenopausal osteoporosis
- Discontinued Cancer pain
Most Recent Events
- 24 Nov 2022 Taisho Pharmaceutical acquires Ibandronic acid (Bonviva®) from Roche and Chugai Pharmaceutical
- 06 Sep 2022 No development reported - Phase-III for Postmenopausal osteoporosis (In the elderly, In adults) in Denmark, Spain, Italy, Germany, Czech Republic, Hungary, United Kingdom (IV) (NDR Batch 23)
- 31 Jul 2020 Roche completes a phase-III clinical trials in Postmenopausal osteoporosis (In adults, In the elderly) in Denmark, Italy, Germany, Czech Republic, Hungary and United Kingdom (IV) (EudraCT2004-002570-32) (IV)