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Drug Profile


Alternative Names: BIRR 0001; BIRR 1; Murine anti-CD54 monoclonal antibody; Murine anti-ICAM-1 monoclonal antibody; R6 5 D6; R6.5; RR1; RR1/1

Latest Information Update: 18 Dec 2001

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At a glance

  • Originator Boehringer Ingelheim
  • Class Monoclonal antibodies
  • Mechanism of Action Immunosuppressants; Intercellular adhesion molecule 1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Asthma; Autoimmune disorders; Burns; Diabetes mellitus; Graft-versus-host disease; Intracranial thrombosis; Liver transplant rejection; Myocardial ischaemia; Renal transplant rejection; Rheumatoid arthritis; Stroke

Most Recent Events

  • 18 Dec 2001 A study has been added to the adverse events and Neurological Disorders therapeutic trials sections
  • 10 May 1999 Results of a clinical study were added to the adverse events and therapeutic trials sections
  • 03 Feb 1999 A study has been added to the Neurological disorders pharmacodynamics section
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