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Eniluracil - Processa Pharmaceuticals

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Drug Profile

Eniluracil - Processa Pharmaceuticals

Alternative Names: 5-Ethynyluracil; 5-EU; 776C85; ADH 300004; GW 776C85; NGC-Cap; NGC-Capecitabine; PCS-6422

Latest Information Update: 18 Sep 2025

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At a glance

  • Originator GlaxoSmithKline
  • Developer Adherex Technologies; Fennec Pharmaceuticals; GlaxoSmithKline; Processa Pharmaceuticals
  • Class Antineoplastics; Chemosensitisers; Pyrimidinones; Small molecules
  • Mechanism of Action Dihydropyrimidine dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Breast cancer
  • Phase I Colorectal cancer; Liver cancer; Pancreatic cancer; Solid tumours
  • No development reported Chemotherapy-induced damage; Gastrointestinal cancer
  • Discontinued Erythrodysaesthesia; Head and neck cancer; Prostate cancer

Most Recent Events

  • 30 May 2025 Efficacy, pharmacokinetics and adverse event data from a phase Ib trial in Gastrointestinal cancer presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 28 Sep 2024 No recent reports of development identified for preclinical development in Chemotherapy-induced-damage in USA (PO)
  • 28 Sep 2024 No recent reports of development identified for preclinical development in Colorectal-cancer(Combination therapy) in USA (PO)

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