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Rosiglitazone - GlaxoSmithKline

Drug Profile

Rosiglitazone - GlaxoSmithKline

Alternative Names: Avandia; BRL 49653; BRL 49653C; Rosiglitazone extended-release; Rosiglitazone maleate; Rosiglitazone XR; RSG XR

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator GlaxoSmithKline
  • Developer Bristol-Myers Squibb; GlaxoSmithKline; GSK
  • Class Antidementias; Antihyperglycaemics; Antipsoriatics; Small molecules; Thiazolidinediones
  • Mechanism of Action Antioxidants; Peroxisome proliferator-activated receptor agonists; Peroxisome proliferator-activated receptor gamma agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Type 2 diabetes mellitus
  • No development reported Asthma
  • Discontinued Alzheimer's disease; Psoriasis; Rheumatoid arthritis

Most Recent Events

  • 25 Nov 2013 US FDA removes restrictions for use of rosiglitazone-containing drugs in Type 2 diabetes mellitus in the USA
  • 06 Jun 2013 Joint advisory committee to the FDA recommends that rosiglitazone remain available to appropriate patients in USA
  • 18 May 2011 The US FDA places further restrictions on rosiglitazone-containing drugs
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