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Drug Profile


Alternative Names: DC 113; DC 88A; DUMs; Duocarmycin; KW 2189; Pibrozelesin hydrobromide

Latest Information Update: 01 Feb 2008

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At a glance

  • Originator Kyowa Hakko
  • Developer GlaxoSmithKline; Janssen L.P.; Kyowa Hakko
  • Class Cytostatic antibiotics; Small molecules
  • Mechanism of Action DNA inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Cancer; Gastric cancer; Pancreatic cancer; Renal cancer

Most Recent Events

  • 12 Jul 2005 Corixa Corporation has been acquired and merged into GlaxoSmithKline
  • 30 Jan 2001 Coulter Pharmaceutical has been acquired by Corixa Corporation
  • 27 Oct 2000 A phase II study has been added to the Cancer adverse events section
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