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Tafenoquine - GlaxoSmithKline/60 Degrees Pharmaceuticals

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Drug Profile

Tafenoquine - GlaxoSmithKline/60 Degrees Pharmaceuticals

Alternative Names: 60P 003; Arakoda; Etaquine; KODATEF; Kozenis; Krintafel; SB-252263; SB-252263-AAB; SB-252263-AX; Tafenoquine maleate; Tafenoquine succinate; WR 238605; WR 238605 succinate

Latest Information Update: 26 Dec 2024

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At a glance

  • Originator Walter Reed Army Institute of Research
  • Developer 60 Degrees Pharmaceuticals; Biocelect; GlaxoSmithKline; GSK; Medicines for Malaria Venture
  • Class Aminoquinolines; Antifungals; Antimalarials; Antiprotozoals; Antivirals; Ethers; Fluorinated hydrocarbons; Small molecules
  • Mechanism of Action Electron transport complex III inhibitors; Reactive oxygen species stimulants; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Babesiosis
  • New Molecular Entity Yes
  • Available For Licensing Yes - COVID 2019 infections

Highest Development Phases

  • Marketed Malaria
  • Phase II Babesiosis; COVID 2019 infections
  • Preclinical Mycoses
  • Discontinued Pneumocystis pneumonia

Most Recent Events

  • 23 Dec 2024 60 Degrees Pharmaceuticals and Tufts Medical Center agree to co-develop Tafenoquine for Babesiosis
  • 16 Dec 2024 60 Degrees Pharmaceuticals and Brigham and Women’s Hospital enter into a clinical trial agreement to expands phase II clinical trial for Babesiosis in Brigham and Women’s Hospital
  • 04 Dec 2024 WHO prequalifies single-dose medicine tafenoquine for Malaria (In adolescents, In children, In adults, In the elderly, Prevention of relapse) and includes in WHO guidelines in South America (PO)

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