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Tezampanel - Proniras

Drug Profile

Tezampanel - Proniras

Alternative Names: LY 293558; NGX 424

Latest Information Update: 07 May 2018

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At a glance

  • Originator Eli Lilly
  • Developer Proniras Corporation; Raptor Pharmaceutical Corp
  • Class Analgesics; Antimigraines; Isoquinolines; Tetrazoles
  • Mechanism of Action AMPA receptor antagonists; Kainic acid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Seizures
  • Discontinued Migraine; Neuromuscular disorders; Thrombosis

Most Recent Events

  • 27 Apr 2018 Tezampanel licensed to Proniras worldwide
  • 27 Apr 2018 Preclinical trials in Seizures in USA (Parenteral) ,
  • 27 Apr 2018 Proniras intends to file an IND with the US FDA for Seizures (nerve agent induced) in 2020
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