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Tezampanel - Proniras

Drug Profile

Tezampanel - Proniras

Alternative Names: LY 293558; NGX 424; PRN-001-01

Latest Information Update: 06 Feb 2024

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At a glance

  • Originator Eli Lilly and Company
  • Developer Indiana University School of Medicine; Proniras Corporation; Raptor Pharmaceutical Corp
  • Class Analgesics; Antiepileptic drugs; Antimigraines; Antithrombotics; Drug withdrawal therapies; Isoquinolines; Tetrazoles
  • Mechanism of Action AMPA receptor antagonists; Kainic acid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Opioid-related disorders
  • No development reported Seizures
  • Discontinued Migraine; Neuromuscular disorders; Thrombosis

Most Recent Events

  • 01 Feb 2024 Proniras Corporation plans a phase I trial for Opioid related disorders (Parenteral)
  • 28 May 2022 No recent reports of development identified for preclinical development in Seizures in USA (Parenteral)
  • 17 Sep 2020 Proniras Corporation plans clinical trials for opioid addiction
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