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Eflornithine/sulindac - Panbela Therapeutics

Drug Profile

Eflornithine/sulindac - Panbela Therapeutics

Alternative Names: CPP-1X/sul; CPP-1X/sulindac; CPP1-x/sulindac; Flynpovi; Sulindac/CPP-1X; Sulindac/eflornithine - Panbela Therapeutics; TP 09

Latest Information Update: 09 May 2024

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At a glance

  • Originator University of Arizona; University of California at Irvine
  • Developer Cancer Prevention Pharmaceuticals; National Cancer Institute (USA); Panbela Therapeutics
  • Class Antineoplastics; Basic amino acids; Diamino amino acids; Indenes; Nonsteroidal anti-inflammatories; Small molecules
  • Mechanism of Action Cyclooxygenase inhibitors; Ornithine decarboxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer; Familial adenomatous polyposis
  • New Molecular Entity No

Highest Development Phases

  • Preregistration Familial adenomatous polyposis
  • Phase III Colorectal cancer
  • No development reported Pancreatic cancer

Most Recent Events

  • 06 May 2024 Panbela Therapeutics has patent protection for eflornithine and sulindac in the US and Canada
  • 05 Sep 2023 Panbela Therapeutics receives patent protection for production process of eflornithine/sulindac in Chile
  • 05 Sep 2023 Panbela Therapeutics has patent pending for eflornithine/sulindac in multiple countries
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