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Nitisinone - Swedish Orphan Biovitrum

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Drug Profile

Nitisinone - Swedish Orphan Biovitrum

Alternative Names: NTBC; Orfadin; SC 0735; SYN-118

Latest Information Update: 12 Apr 2024

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At a glance

  • Originator Syngenta
  • Developer Biotie Therapies Corp.; Swedish Orphan Biovitrum
  • Class Antiparkinsonians; Cyclohexanones; Nitrobenzoates; Small molecules
  • Mechanism of Action 4-hydroxyphenylpyruvate dioxygenase inhibitors; Dopamine release stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Tyrosinaemia type I
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Inborn error metabolic disorders; Tyrosinaemia type I
  • Discontinued Parkinson's disease

Most Recent Events

  • 31 Dec 2023 Launched for Tyrosinaemia type I (In children, In infants, In adults) in Brazil (PO) prior to December 2023
  • 31 Dec 2023 Launched for Tyrosinaemia type I in Saudi Arabia (PO) prior to December 2023
  • 31 Dec 2023 Registered for Tyrosinaemia type I in China (PO) prior to December 2023

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