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Alpha 1 antitrypsin modified process - Grifols

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Drug Profile

Alpha 1 antitrypsin modified process - Grifols

Alternative Names: Alpha-1 MP - Grifols; Alpha-1 proteinase-inhibitor-modified process - Grifols; Alpha-1-antitrypsin IV - Grifols; Alpha-1-protease-inhibitor-modified process - Grifols; Alpha-antitrypsin modified process - Grifols; Alpha1-PI; Lynspad; Prolastin; Prolastin-C; Prolastin-C Liquid; Prolastina; Pulmolast; TAL 6004

Latest Information Update: 18 Dec 2025

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At a glance

  • Originator Bayer
  • Developer CSL Vifor; Grifols
  • Class Acute-phase proteins; Alpha globulins; Anti-inflammatories; Antiallergics; Antihyperglycaemics; Blood proteins; Enzymes; Secretory proteinase inhibitory proteins; Serpins
  • Mechanism of Action Immunomodulators; Serine endopeptidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Alpha 1-antitrypsin deficiency
  • New Molecular Entity No

Highest Development Phases

  • Marketed Alpha 1-antitrypsin deficiency
  • Phase II COVID 2019 infections; Type 1 diabetes mellitus
  • Discontinued Chronic fatigue syndrome

Most Recent Events

  • 18 Dec 2025 Grifols announces intention to submit an IND application for a phase III trial in Alpha 1-antitrypsin deficiency (SC, Injection) in 2026
  • 04 Nov 2025 Grifols plans a phase III trial for Alpha 1-antitrypsin deficiency (SC, Injection)
  • 04 Nov 2025 Discontinued - Phase-II for Chronic fatigue syndrome (In adults, In the elderly) in Spain (IV) before November 2025

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