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Alicaforsen - Atlantic Healthcare

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Drug Profile

Alicaforsen - Atlantic Healthcare

Alternative Names: Alicaforsen enema; Alicaforsen sodium; AP 1007; AP 1431; AP 1450; AP 1451; Camligo; ISIS 2302

Latest Information Update: 05 Sep 2022

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Atlantic Healthcare
  • Class Anti-inflammatories; Antipsoriatics; Antisense oligonucleotides; Thionucleotides
  • Mechanism of Action Immunosuppressants; Intercellular adhesion molecule-1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pouchitis
  • New Molecular Entity Yes
  • Available For Licensing Yes - Crohn's disease; Pouchitis; Ulcerative colitis

Highest Development Phases

  • Phase III Crohn's disease
  • Phase II Ulcerative colitis
  • No development reported Pouchitis
  • Discontinued Asthma; Inflammation; Psoriasis; Renal transplant rejection; Rheumatoid arthritis

Most Recent Events

  • 15 Aug 2022 Ionis Pharmaceuticals completes phase III clinical trials in Crohn's disease in Belgium, Czech Republic, Germany, Italy, Poland, Spain (IV) (NCT00048295)
  • 02 Feb 2022 Atlantic Healthcare has patent protection for Alicaforsen in USA for the treatment of inflammatory bowel disease
  • 03 Oct 2021 Updated adverse events, efficacy and pharmacokinetics data from a phase III trial in Pouchitis presents at the 29th United European Gastroenterology Week (UEGW-2021)

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