Alicaforsen - Atlantic Healthcare

Drug Profile

Alicaforsen - Atlantic Healthcare

Alternative Names: Alicaforsen sodium; AP 1007; AP 1431; AP 1450; AP 1451; ISIS 2302

Latest Information Update: 08 May 2018

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Atlantic Healthcare
  • Class Anti-inflammatories; Antipsoriatics; Antisense oligonucleotides; Thionucleotides
  • Mechanism of Action Immunosuppressants; Intercellular adhesion molecule 1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pouchitis
  • New Molecular Entity Yes
  • Available For Licensing Yes - Crohn's disease; Pouchitis; Ulcerative colitis

Highest Development Phases

  • Preregistration Pouchitis
  • Phase III Ulcerative colitis
  • Preclinical Crohn's disease
  • Discontinued Asthma; Inflammation; Psoriasis; Renal transplant rejection; Rheumatoid arthritis

Most Recent Events

  • 02 May 2018 Atlantic Healthcare completes enrolment in its phase III trial for Pouchitis in USA, Belgium, Canada, France, Ireland, Israel, Italy, Netherlands, Switzerland and United Kingdom (Topical)
  • 16 Mar 2018 Atlantic Pharmaceuticals initiates a phase I pharmacokinetic trial in Healthy volunteers in United Kingdom (PO) (NCT03473626)
  • 18 Sep 2017 Atlantic Pharmaceuticals initiates enrolment a phase III trial in France, Italy, Ireland, Netherlands, and United Kingdom after December 2015 (NCT02525523)
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