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Drug Profile


Alternative Names: Virulizin

Latest Information Update: 04 Jun 2015

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At a glance

  • Originator Lorus Therapeutics
  • Developer Aptose Biosciences
  • Class Antineoplastics
  • Mechanism of Action Interleukin 17 stimulants; Tumour necrosis factor stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Malignant melanoma
  • Discontinued Breast cancer; Cervical cancer; Colorectal cancer; Gastric cancer; Kaposi's sarcoma; Lung cancer; Ovarian cancer; Pancreatic cancer; Prostate cancer; Renal cancer; Uterine cancer

Most Recent Events

  • 04 Jun 2015 Discontinued - Phase-III for Pancreatic cancer in USA, Brazil, Canada, Czech Republic, Hungary, Mexico, Poland, Romania, Russia, Spain and Ukraine (IM)
  • 02 Sep 2014 Lorus Therapeutics is now called Aptose Biosciences
  • 08 Apr 2008 Virulizin® licensed to ZOR Pharmaceuticals in Central, North and South America, Europe and Israel for the treatment of pancreatic cancer and other human therapeutic applications
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