Palonosetron intravenous - Helsinn Healthcare
Alternative Names: 2-QHBIQO; Aloxi Injection; Nuowei; ONICIT; Onicit; Palonosetron hydrochloride; Paloxi; RS-25259; RS-25259-197; RS-42358-197Latest Information Update: 16 Feb 2026
At a glance
- Originator Roche Palo Alto LLC
- Developer Helsinn; HK inno.N; Knight Therapeutics; Taiho Pharmaceutical
- Class Antiemetics; Isoquinolines; Quinuclidines; Small molecules
- Mechanism of Action Serotonin 3 receptor antagonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Chemotherapy-induced nausea and vomiting; Postoperative nausea and vomiting
Most Recent Events
- 11 Feb 2026 Palonosetron licensed to MagnaPharm in Poland, Romania, Czech Republic, Slovakia and Hungary
- 10 Feb 2026 Helsinn Healthcare extends licensing of palonosetron to ESTEVE in Austria
- 07 May 2025 Launched for Chemotherapy-induced nausea and vomiting (In infants, In children, In adolescents, In adults) in Brazil (IV) prior to May 2025