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Argatroban - Mitsubishi Chemical

Drug Profile

Argatroban - Mitsubishi Chemical

Alternative Names: Acova; Arganova; Argatra; Argipidine; Da Bei; DK 7419; Exembol; GN 1600; MCI-9038; MD 805; Novastan; OM 805; Slonnon

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Mitsubishi Chemical
  • Developer Correvio Pharma; Daiichi Sankyo Company; Mitsubishi Tanabe Pharma Corporation; Mitsubishi Tanabe Pharma Europe; Novartis; University of Texas Health Science Center at Houston
  • Class Anti-ischaemics; Anticoagulants; Antithrombotics; Carboxylic acids; Imines; Ischaemic heart disorder therapies; Pipecolic acids; Piperidines; Quinolines; Small molecules; Sulfones; Vascular disorder therapies
  • Mechanism of Action Thrombin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Heparin-induced thrombocytopenia and thrombosis syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Arterial thrombosis; Heparin-induced thrombocytopenia and thrombosis syndrome; Peripheral arterial occlusive disorders; Stroke
  • Registered Intracranial thrombosis
  • Discontinued Myocardial infarction; Unstable angina pectoris

Most Recent Events

  • 08 Apr 2021 Discontinued - Phase-II for Stroke (Combination therapy) in United Kingdom (IV) (EudraCT2012-002319-25)
  • 08 Apr 2021 Discontinued - Phase-II for Stroke (Combination therapy) in USA (IV) (NCT01464788)
  • 01 Mar 2021 Daiichi Sankyo Company plans to transfer rights of Slonnon to Alfresa Pharma by December 2021
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