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Suramin sodium

Drug Profile

Suramin sodium

Alternative Names: Antrypol; Bayer 205; CI 1003; Germanin; Metaret; Moranyl; Suramin; Suramin hexasodium

Latest Information Update: 22 Jan 2019

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At a glance

  • Originator Bayer
  • Developer Austrian Academy of Sciences; Bayer; National Cancer Institute (USA); Optimum Therapeutics; Pfizer; The First Affiliated Hospital of Zhengzhou University; University of California, San Diego; University of Wisconsin-Madison
  • Class Antiprotozoals; Naphthalenesulfonates
  • Mechanism of Action DNA-directed DNA polymerase inhibitors; Intercellular signalling peptide and protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Phase I/II Pervasive child development disorders
  • Phase I Enterovirus A infections
  • Discontinued Atherosclerosis; Bladder cancer; Breast cancer; Cancer pain; HIV infections; Prostate cancer; Vascular restenosis

Most Recent Events

  • 19 Dec 2018 Phase-I clinical trials in Enterovirus A infections (In volunteers) in China (IV) (NCT03804749)
  • 24 Jun 2018 Biomarkers information updated
  • 01 May 2015 Phase-I/II clinical trials in Pervasive child development disorders in USA (IV-infusion)
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