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Infliximab - Janssen Biotech

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Drug Profile

Infliximab - Janssen Biotech

Alternative Names: cA2; CenTNF; Remicade; TA-650

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator NYU Langone Medical Center
  • Developer Centocor; Janssen Biotech; Merck & Co; Mitsubishi Tanabe Pharma Corporation; National Jewish Medical and Research Center; Xian-Janssen
  • Class Anti-inflammatories; Anti-TNF monoclonal antibodies; Antipsoriatics; Antirheumatics
  • Mechanism of Action Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mucocutaneous lymph node syndrome; Crohn's disease; Juvenile rheumatoid arthritis; Ankylosing spondylitis; Behcet's syndrome; Sarcoidosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ankylosing spondylitis; Behcet's syndrome; Crohn's disease; Mucocutaneous lymph node syndrome; Plaque psoriasis; Psoriasis; Psoriatic arthritis; Rheumatoid arthritis; Ulcerative colitis
  • Phase III COVID 2019 infections
  • Discontinued Berylliosis; Hepatitis C; Pyoderma

Most Recent Events

  • 19 Oct 2022 Efficacy and adverse event data from the Phase III ACTIV-1 trial in COVID-2019 infections presented at the IDWeek 2022
  • 05 Mar 2022 Duke University in collaboration with Janssen completes the phase III ACTIV-1 trial in COVID-19 infections in USA, Argentina, Brazil, Mexico, Peru (IV) (NCT04593940)
  • 02 Jul 2019 Infliximab is not yet available for Crohn's disease and Ulcerative colitis in Taiwan

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