Vinorelbine - Pierre Fabre

Drug Profile

Vinorelbine - Pierre Fabre

Alternative Names: KW-2307; Navelbine; NVB; Vinorelbine ditartrate; Vinorelbine tartrate

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator CNRS
  • Developer Amgen; Bristol-Myers Squibb; Centre Oscar Lambret; Pierre Fabre; University of Washington
  • Class Antineoplastics; Small molecules; Vinca alkaloids
  • Mechanism of Action Mitosis inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer; Non-small cell lung cancer
  • Phase II Glioma; Mesothelioma
  • No development reported Cervical cancer; Head and neck cancer; Malignant melanoma; Ovarian cancer; Prostate cancer; Small cell lung cancer
  • Discontinued Multiple myeloma

Most Recent Events

  • 30 Jan 2018 Pfizer plans the phase II AVIATOR trial for Breast Cancer in the US, (NCT03414658)
  • 12 Jan 2018 Pierre Fabre terminates a phase II trial due to low recruitment in Non-small cell lung cancer (Late-stage disease, Metastatic disease, First-line therapy, Combination therapy) in Italy (IV) (NCT02919462)
  • 05 Dec 2017 Adverse events and efficacy data from a phase II trial in Breast cancer presented at the 40th Annual San Antonio Breast Cancer Symposium (SABCS-2017)
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