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Vinorelbine - Pierre Fabre

Drug Profile

Vinorelbine - Pierre Fabre

Alternative Names: KW-2307; Navelbine; NVB; Vinorelbine ditartrate; Vinorelbine tartrate

Latest Information Update: 19 Aug 2019

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At a glance

  • Originator CNRS
  • Developer Amgen; Bristol-Myers Squibb; Centre Oscar Lambret; Pierre Fabre; UNICANCER; University of Washington
  • Class Antineoplastics; Small molecules; Vinca alkaloids
  • Mechanism of Action Mitosis inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Breast cancer; Non-small cell lung cancer
  • Phase II Glioma; Mesothelioma
  • Phase I/II Solid tumours
  • No development reported Cervical cancer; Head and neck cancer; Malignant melanoma; Ovarian cancer; Prostate cancer; Small cell lung cancer
  • Discontinued Multiple myeloma

Most Recent Events

  • 07 Aug 2019 Pierre Fabre terminates phase II trial in Breast cancer in Spain (EudraCT2016-002674-12)
  • 20 Jun 2018 Phase-I/II clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in France (PO) (NCT03518606)
  • 01 Jun 2018 Adverse events and efficacy data from phase II NAVoTRIAL-3 trial in Nono-small cell lung cancer presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
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