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Monoclonal antibody 3F8

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Drug Profile

Monoclonal antibody 3F8

Alternative Names: 3F8 MAb; MAb-3F8; MOAB 3F8; Murine 3F8 monoclonal antibody

Latest Information Update: 24 Oct 2021

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Neuroblastoma
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cancer; Neuroblastoma

Most Recent Events

  • 10 Mar 2010 Phase-II development is ongoing in USA
  • 31 Dec 2007 Monoclonal antibody 3F8 licensed to United Therapeutics Corporation worldwide
  • 31 Jan 2007 Memorial Sloan-Kettering Cancer Center initiates enrolment in a phase II trial for neuroblastoma in the US

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