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Clodronic acid

Drug Profile

Clodronic acid

Alternative Names: 177501; Ascredar; Bonefos; Bonephos; CL-I.A.; Cl2MDP; Clasteon; Clastoban; Climaclod; Clodeosten; Clodron; Clodron beta; Clodronate; Clodronate disodium; Clody; Difosfonal; Dolkin; Hemocalcin; KCO 692; Lodronat; Loron; Lytos; Mebonat; Moticlod; Nikclod; Ossiten; Ostac; Osteonorm; Osteostab; Sindronat; ZK 00091106

Latest Information Update: 07 May 2019

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At a glance

  • Originator Schering Oy
  • Developer Abiogen Pharma; Bayer HealthCare Pharmaceuticals; Roche; Schering Oy
  • Class Antihypercalcaemics; Antirheumatics; Bisphosphonates; Calcium regulators; Osteoporosis therapies; Small molecules
  • Mechanism of Action Bone resorption factor inhibitors; Collagen stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bone metastases; Malignant hypercalcaemia; Postmenopausal osteoporosis
  • Phase II Osteoarthritis

Most Recent Events

  • 14 Mar 2019 Phase-II clinical trials in Osteoarthritis in Czech Republic (Intra-articular) (EudraCT 2018-002081-39)
  • 24 Jun 2018 Biomarkers information updated
  • 17 Jan 2018 No development reported - Phase-III for Osteoarthritis in Italy (Intra-articular)
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