Afamelanotide - Clinuvel Pharmaceuticals

Drug Profile

Afamelanotide - Clinuvel Pharmaceuticals

Alternative Names: [Nle4,DPhe7]-alpha-MSH; CUV-1647; EPT-1647; Melanotan I; Melanotan™; MT I; Scenesse

Latest Information Update: 24 Aug 2018

Price : $50 *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator University of Arizona
  • Developer Clinuvel Pharmaceuticals
  • Class Antineoplastics; Antipyretics; Melanocyte-stimulating hormones; Peptides; Skin disorder therapies
  • Mechanism of Action Melanin stimulants; Melanocortin type 1 receptor agonists; Melanocyte modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Erythropoietic protoporphyria; Pemphigus; Urticaria
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Erythropoietic protoporphyria
  • Phase II Pemphigus; Vitiligo
  • Suspended Photodamage; Polymorphus light eruptions; Urticaria
  • Discontinued Acne vulgaris; Actinic keratosis; Squamous cell cancer

Most Recent Events

  • 25 Jun 2018 Clinuvel Pharmaceuticals expects the review for afamelanotide's NDA in Erythropoietic protoporphyria (Prevention) in USA (SC) to be completed in 2019
  • 25 Jun 2018 The US FDA begins a review of afamelanotide's NDA in Erythropoietic protoporphyria (Prevention) in USA (SC)
  • 25 Jun 2018 Preregistration for Erythropoietic protoporphyria (Prevention) in USA (SC)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top