Gemtuzumab ozogamicin - Pfizer
Alternative Names: Anti-CD33-monoclonal-antibody-calicheamicin; Anti-CD33-monoclonal-antibody-p67-6-calicheamicin-conjugate; CDP-771; CMA-676; Gemtuzumab; HP67-6-N-acetyl-gamma-dimethyl-acbut; Human-anti-CD33-monoclonal-antibody-P67-6-calicheamicin-conjugate; MYLOTARG; Mylotarg; WAY-CMA-676Latest Information Update: 25 Jul 2024
At a glance
- Originator UCB
- Developer National Cancer Institute (USA); Pfizer; Technische Universitat Dresden
- Class Aminoglycosides; Antineoplastics; Cytostatic antibiotics; Drug conjugates; Immunoconjugates; Monoclonal antibodies
- Mechanism of Action DNA damage stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Acute myeloid leukaemia
Most Recent Events
- 11 Jul 2024 OHSU Knight Cancer Institute and Pfizer re-initiates enrolment in a phase I trial for Acute myeloid leukemia (Combination therapy, Newly diagnosed, First-line therapy) in the US (NCT03900949)
- 22 May 2024 OHSU Knight Cancer Institute and Pfizer suspends a phase I trial due to accrual goal for Acute myeloid leukemia (Combination therapy, Newly diagnosed, First-line therapy) in the US (NCT03900949)
- 27 Apr 2023 9387040- No updates