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Tenecteplase - Genentech

Drug Profile

Tenecteplase - Genentech

Alternative Names: Metalyse; Recombinant tissue plasminogen activator-Genentech; RG-3625; TNK; TNK-tPA; TNKase

Latest Information Update: 10 Jul 2019

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At a glance

  • Originator Genentech
  • Developer Boehringer Ingelheim; Genentech; Roche Canada
  • Class Blood coagulation factors; Plasminogen activator enzymes; Serine endopeptidases; Thrombolytics
  • Mechanism of Action Plasminogen activators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Myocardial infarction
  • Phase III Stroke
  • Discontinued Catheter thrombosis; Heart arrest

Most Recent Events

  • 29 Apr 2019 Phase-III clinical trials in Stroke in Canada (IV) (NCT03785678)
  • 29 Apr 2019 Phase-III clinical trials in Stroke in USA (IV)
  • 24 Dec 2018 Genentech plans the phase III TIMELESS trial for Stroke in USA (IV) (NCT03785678)
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