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Cetuximab - Eli Lilly and Company

Drug Profile

Cetuximab - Eli Lilly and Company

Alternative Names: Anti-EGFR monoclonal antibody 225; C 225; ch 225; Erbitux; IMC-C225; LY-2939777

Latest Information Update: 09 Dec 2019

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At a glance

  • Originator University of California
  • Developer Array BioPharma; Bristol-Myers Squibb; Celldex Therapeutics Inc; Centre Jean Perrin; Eli Lilly; Eli Lilly and Company; Merck KGaA; New York University School of Medicine; Novartis; Pierre Fabre; Roche; UNICANCER; University Hospital Ghent; University of Heidelberg; University of Michigan Comprehensive Cancer Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Angiogenesis inhibitors; Antibody-dependent cell cytotoxicity; Epidermal growth factor receptor antagonists; T lymphocyte inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Colorectal cancer; Head and neck cancer
  • Phase III Non-small cell lung cancer
  • Phase II Bladder cancer; Breast cancer; Gastric cancer; Mesothelioma; Rectal cancer; Squamous cell cancer
  • Phase I/II Adenoid cystic carcinoma; Solid tumours
  • Phase Unknown Oesophageal cancer
  • No development reported Pancreatic cancer; Prostate cancer

Most Recent Events

  • 02 Dec 2019 Phase-I/II clinical trials in Solid tumours (Combination therapy, Late-stage disease, Second-line therapy or greater) in Spain, Canada, Australia, USA (IV) (NCT04165031)
  • 30 Nov 2019 UNICANCER completes a phase-I/II clinical trials in Squamous cell cancer (Recurrent, Metastatic disease, Combination therapy, Late-stage disease, Second-line therapy or greater) in France (IV) (NCT02822482) (EudraCT2015-004340-19)
  • 19 Nov 2019 Eli Lilly and Company plans a phase I/II trial for Solid tumours (Combination therapy, Late-stage disease, Second-line therapy or greater) in USA, Australia, Canada, Spain (IV) (NCT04165031)
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