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Cetuximab - Eli Lilly

Drug Profile

Cetuximab - Eli Lilly

Alternative Names: Anti-EGFR monoclonal antibody 225; C 225; ch 225; Erbitux; IMC-C225; LY-2939777

Latest Information Update: 17 Jan 2019

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At a glance

  • Originator University of California System
  • Developer Array BioPharma; Bristol-Myers Squibb; Celldex Therapeutics Inc; Centre Jean Perrin; Eli Lilly; Merck KGaA; New York University School of Medicine; Novartis; Pierre Fabre; Roche; University Hospital Ghent; University of Heidelberg; University of Michigan Comprehensive Cancer Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Colorectal cancer; Head and neck cancer
  • Phase III Non-small cell lung cancer
  • Phase II Bladder cancer; Breast cancer; Gastric cancer; Mesothelioma; Rectal cancer; Squamous cell cancer
  • Phase I/II Adenoid cystic carcinoma
  • Phase Unknown Oesophageal cancer
  • No development reported Pancreatic cancer; Prostate cancer

Most Recent Events

  • 17 Jan 2019 Updated efficacy and adverse events data from the phase III BEACON CRC trial in Colorectal cancer released by Array Biopharma
  • 19 Dec 2018 Phase-II clinical trials in Squamous cell cancer (Late-stage disease, Combination therapy) in Germany (IV) (EudraCT2018-001708-12)
  • 31 Aug 2018 Phase-II clinical trials in Non-small cell lung cancer (Late-stage disease, Combination therapy, Recurrent, Metastatic disease) in Spain, Hungary (IV) (EudraCT2018-001529-24)
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