Antithymocyte globulin - Sanofi
Alternative Names: anti-thymocyte globulin; anti-thymocyte globulin (rabbit); Antithymocyte immunoglobulin; ATG; Polyclonal rabbit antithymocyte globulin; Rabbit antithymocyte globulin; Rabbit-ATG; rATG; Thymoglobulin; ThymoglobulineLatest Information Update: 05 Nov 2023
At a glance
- Originator sanofi pasteur
- Developer Cedars-Sinai Medical Center; National Institute of Diabetes and Digestive and Kidney Diseases; Sanofi; University of Texas M. D. Anderson Cancer Center; Virginia Commonwealth University
- Class Polyclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; Immunosuppressants
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Aplastic anaemia; Bone marrow transplant rejection; Graft-versus-host disease; Liver transplant rejection; Pancreas transplant rejection; Renal transplant rejection; Transplant rejection
- Phase II Heart transplant rejection; Myelodysplastic syndromes; Type 1 diabetes mellitus
Most Recent Events
- 19 Oct 2020 Phase II development is still ongoing Heart transplant rejection (Prevention) in USA (IV) (NCT03292861)
- 16 Jul 2019 Sanofi Company completes a phase I/II trial in Type-1 diabetes mellitus (Combination therapy) in USA (IV) (NCT01106157)
- 23 Oct 2018 No development reported - Phase-II for Liver transplant rejection (Combination therapy, Prevention) in USA (IV)