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Drug Profile


Alternative Names: BPI 21; Neuprex; rBPI21; Recombinant bactericidal permeability increasing protein 21

Latest Information Update: 03 Aug 2010

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At a glance

  • Originator New York University
  • Developer XOMA
  • Class Antibacterials; Recombinant proteins
  • Mechanism of Action Angiogenesis inhibitors; Cell membrane permeability enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Meningococcal infections

Highest Development Phases

  • No development reported Meningococcal infections; Postoperative infections; Radiation injuries; Wound infections
  • Discontinued Graft-versus-host disease; Post-traumatic infections

Most Recent Events

  • 03 Aug 2010 Discontinued - Phase-I/II for Graft-versus-host disease in USA (Parenteral)
  • 09 Jan 2007 Phase-I/II clinical trials in Graft-versus-host disease in USA (Parenteral)
  • 06 Sep 2006 Opebacan has received orphan drug status for Meningococcal infections in the European Union
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