Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?


Drug Profile


Alternative Names: BPI 21; Neuprex; rBPI21; Recombinant bactericidal permeability increasing protein 21

Latest Information Update: 24 Oct 2021

Price : $50 *
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator New York University
  • Developer XOMA
  • Class Antibacterials; Recombinant proteins
  • Mechanism of Action Angiogenesis inhibitors; Cell membrane permeability enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Meningococcal infections

Highest Development Phases

  • No development reported Meningococcal infections; Postoperative infections; Radiation injuries; Wound infections
  • Discontinued Graft-versus-host disease; Post-traumatic infections

Most Recent Events

  • 03 Aug 2010 Discontinued - Phase-I/II for Graft-versus-host disease in USA (Parenteral)
  • 09 Jan 2007 Phase-I/II clinical trials in Graft-versus-host disease in USA (Parenteral)
  • 06 Sep 2006 Opebacan has received orphan drug status for Meningococcal infections in the European Union
Subscriber content

You need to be a logged in subscriber to view this content.

If your organization has a subscription then there are several options available to help you access AdisInsight, even while working remotely.

  • IP authentication when working within your organization’s network.
  • with username/password or try via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days.
  • Contact us at AsktheExpert.AdisInsight@springer.com for assistance.

If your organization does not have a subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Buy a PDF version of the profile.
  • Request a free trial
Back to top