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Drug Profile


Alternative Names: Diclofenac + HA topical; Hyaluronic acid + diclofenac; Hyanalgese-D; Oralease

Latest Information Update: 11 Dec 2007

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At a glance

  • Originator SkyePharma Inc
  • Developer Pacira Pharmaceuticals; SkyePharma Inc; Symbion Health
  • Class Glycosaminoglycans; Nonsteroidal anti-inflammatories; Phenylacetates
  • Mechanism of Action Cyclooxygenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Aphthous ulcer pain; Pain; Rheumatic disorders

Most Recent Events

  • 08 Dec 1998 Phase-III clinical trials for Aphthous ulcer pain in USA (Topical)
  • 01 Oct 1998 Hyal Pharmaceutical has acquired the rights to HYAL AT2101 in Asian countries, which had been licensed to its Australian subsidiary
  • 12 Feb 1998 Discontinued-III for Pain in Austria (Topical)
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