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Gallium nitrate - Genta

Drug Profile

Gallium nitrate - Genta

Alternative Names: Calstat; G 4544; G4544a; Ganite; NSC 15200

Latest Information Update: 11 Jul 2018

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center; National Cancer Institute (USA)
  • Developer Cystic Fibrosis Foundation; Emisphere Technologies; Genta (CEASED); University of Washington
  • Class Antihypercalcaemics; Antineoplastics; Calcium regulators; Heavy metals; Small molecules
  • Mechanism of Action Osteoclast inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Market Withdrawal Malignant hypercalcaemia
  • Discontinued Bone cancer; Infections; Non-Hodgkin's lymphoma; Osteitis deformans; Osteoporosis

Most Recent Events

  • 21 Apr 2010 Pharmacokinetics data from a preliminary clinical trial in Cystic-fibrosis associated respiratory tract infections released by Genta
  • 13 Jan 2010 Preclinical pharmacodynamics data in Osteoporosis released by Genta
  • 03 Jun 2008 Interim pharmacokinetics data from a phase I trial presented at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO-2008) ,
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