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Drug Profile


Alternative Names: Betakine; Recombinant transforming growth factor-beta-2; TGF-beta-2; Transforming growth factor-beta-2

Latest Information Update: 15 Dec 2016

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At a glance

  • Originator Insmed
  • Developer Enzon Pharmaceuticals; Genzyme Corporation; Insmed
  • Class Transforming growth factors
  • Mechanism of Action Immunosuppressants; Intercellular signalling peptide and protein stimulants; Osteogenesis stimulants; Transforming growth factor beta2 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Age-related macular degeneration; Autoimmune disorders; Cancer; Diabetic foot ulcer; Eye disorders; Multiple sclerosis; Pleural effusion; Postmenopausal osteoporosis; Rheumatoid arthritis; Skin disorders; Transplant rejection

Most Recent Events

  • 10 Jan 2006 Discontinued - Phase-I for Multiple sclerosis in USA (IV)
  • 10 Jan 2006 Discontinued - Phase-II for Diabetic foot ulcer in USA (unspecified route)
  • 10 Jan 2006 Discontinued - Preclinical for Pleural effusion in Australia (unspecified route)
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