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Drug Profile


Alternative Names: Art 50; Artrodar; Artrolyt; Cartivix; Diacerhein; Diacetylrhein; Fisiodar; Galaxdar; KW 4800; Matrix; Rhein diacetate; SF 277; Verboril

Latest Information Update: 16 Jul 2019

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At a glance

  • Originator Istituto Gentili; Proter
  • Developer Abiogen Pharma; Ecupharma; Faran; Kyowa Kirin; Lacer; Myungmoon Pharm; Neo-Farmaceutica; Neopharmed Gentili; Proter; TRB Pharma; Wockhardt
  • Class Anthraquinones; Anti-inflammatories; Antihyperglycaemics; Antirheumatics; Skin disorder therapies; Small molecules
  • Mechanism of Action Interleukin 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Osteoarthritis

Most Recent Events

  • 10 Feb 2016 TRB Chemedica International plans the phase III/IV DISSCO trial for Osteoarthritis (In adults, In the elderly) in Canada, Spain, Austria and Czech Republic (PO) (NCT02688400)
  • 07 Mar 2014 Pharmacovigilance Risk Assessment Committee recommends restrictions of diacerein availability in Osteoarthritis to manage risk of adverse events in the European Union
  • 04 Mar 2014 Biomarkers information updated
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