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Palifosfamide

Drug Profile

Palifosfamide

Alternative Names: IPM-tris; Isophosphamide mustard-tris; Isophosphoramide mustard; Palifosfamide-tris; ZIO-201; ZIO-201-T; Zymafos

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Dekk-Tec
  • Developer ZIOPHARM Oncology
  • Class Antineoplastics; Cyclophosphamides; Oxazines; Small molecules
  • Mechanism of Action Alkylating agents; DNA cross linking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Small cell lung cancer
  • Phase II Breast cancer; Germ cell and embryonal neoplasms; Ovarian cancer; Testicular cancer
  • No development reported Haematological malignancies; Solid tumours
  • Discontinued Soft tissue sarcoma

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy) in USA (IV)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in USA (IV)
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