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Iobenguane I-131 - Progenics Pharmaceuticals

Drug Profile

Iobenguane I-131 - Progenics Pharmaceuticals

Alternative Names: 131-I-metaiodobenzylguanidine; 131-I-MIGB; 131I-iobenguane - Progenics Pharmaceuticals; 131I-MIBG - Progenics Pharmaceuticals; 3-iodobenzylguanidine-I-123; Azedra; HSA I-131 MIBG; I-131 mIBG; I-131-iobenguane; Iobenguane-I123-injection; Iobenguane-I131; Iobenguane-sulfate; Iodine-123 metaiodobenzylguanidine - Progenics Pharmaceuticals; Iodine-131 iobenguane - Progenics Pharmaceuticals; Iodine-131 metaiodobenzylguanidine - Progenics Pharmaceuticals; Iodine-131-metaiodobenzylguanidine; Iodine-I-131-metaiodobenzylguanidine; m-Iodobenzylguanidine-sulfate; Meta-iodobenzylguanidine; Metaiodobenzylguanidine-I-123; Metaiodobenzylguanidine-I-131; Metaiodobenzylguanidine-sulfate; MIBG; MIP-120T; Ultratrace I-131-MIBG; Ultratrace iobenguane I 131; Ultratrace MIBG; Ultratrace-iobenguane-I-131

Latest Information Update: 11 Feb 2019

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At a glance

  • Originator Molecular Insight Pharmaceuticals
  • Developer Progenics Pharmaceuticals
  • Class Antineoplastics; Guanidines; Iodobenzenes; Radiopharmaceuticals; Small molecules; Sulfates
  • Mechanism of Action Cell death stimulants; Neuron inhibitors; Poly(ADP-ribose) polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Neuroendocrine tumours
  • New Molecular Entity No

Highest Development Phases

  • Marketed Neuroendocrine tumours
  • Phase II Neuroblastoma

Most Recent Events

  • 30 Jan 2019 Molecular Insight Pharmaceuticals completes an expanded-access programme for Neuroendocrine tumours in USA (NCT02961491)
  • 08 Nov 2018 The National Comprehensive Cancer Network recommends iobenguane I 131 for the treatment of neuroendocrine and adrenal tumours (In adolescents, Inoperable/Unresectable, Late-stage disease, Metastatic disease, In adults)
  • 07 Aug 2018 Launched for Neuroendocrine tumours (In adolescents, Inoperable/Unresectable, Late-stage disease, Metastatic disease, In adults) in USA (IV) (Progenics pipeline, August 2018)
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