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Rebamipide - Otsuka Pharmaceutical

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Drug Profile

Rebamipide - Otsuka Pharmaceutical

Alternative Names: MCT-SR; Mucosta; OPC-12759; OPC-12759E; OPC759; Pramipide; Proamipide

Latest Information Update: 20 Nov 2024

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At a glance

  • Originator Otsuka Pharmaceutical
  • Developer Kubota Vision; Otsuka Pharmaceutical
  • Class Amino acids; Anti-inflammatories; Antiulcers; Cytoprotectives; Eye disorder therapies; Quinolones; Small molecules
  • Mechanism of Action Oxygen radical formation antagonists; Oxygen radical scavengers; Prostaglandin agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Dry eyes; Gastric ulcer; Gastritis
  • Phase II Stomatitis
  • Discontinued Cancer; Diabetes mellitus; Keratoconjunctivitis; NSAID-induced ulcer; Ulcerative colitis; Xerostomia

Most Recent Events

  • 20 Nov 2024 No development reported - Phase-III for Gastritis (In the elderly, In adults) in South Korea (PO) (NCT04189705)
  • 28 Aug 2022 No recent reports of development identified for phase-I development in Gastric-ulcer(In volunteers) in South Korea (PO, Controlled release)
  • 11 Mar 2021 Otsuka Pharmaceutical completes a phase III clinical trial in Gastritis (In adults, In the elderly) in South Korea (PO, Controlled release) (NCT04189705)

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