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Oritavancin - Melinta Therapeutics

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Drug Profile

Oritavancin - Melinta Therapeutics

Alternative Names: KIMYRSA; LY-333328; LY-333328 diphosphate; Nuvocid; ORBACTIV; Oritavancin diphosphate; Ramvocid

Latest Information Update: 17 Dec 2025

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At a glance

  • Originator Eli Lilly and Company
  • Developer Melinta Therapeutics; Menarini; The Medicines Company; Xediton Pharmaceuticals
  • Class Antibacterials; Glycopeptides; Peptide antibiotics
  • Mechanism of Action Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Skin and soft tissue infections
  • Phase II Bacteraemia
  • No development reported Gram-positive infections
  • Discontinued Anthrax; Clostridium difficile infections

Most Recent Events

  • 20 Nov 2025 Melinta Therapeutics completes a phase II trial in Skin and soft tissue infections (In adolescents, In children, In infants) in Lithuania, Latvia, Poland, Portugal, Romania, Greece, USA, Bulgaria and Spain (IV) (EudraCT2022-001297-63) (NCT05599295)
  • 02 Sep 2025 Melinta Therapeutics has been acquired by CorMedix
  • 31 Aug 2024 Preregistration for Skin and soft tissue infections in Canada (IV), in August 2024

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