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Oritavancin - Melinta Therapeutics

Drug Profile

Oritavancin - Melinta Therapeutics

Alternative Names: LY-333328; LY-333328 diphosphate; Nuvocid; ORBACTIV; Oritavancin diphosphate; Ramvocid

Latest Information Update: 05 Nov 2018

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At a glance

  • Originator Eli Lilly
  • Developer The Medicines Company
  • Class Antibacterials; Glycopeptides; Peptide antibiotics
  • Mechanism of Action Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Skin and soft tissue infections
  • Phase II Bacteraemia
  • Phase I Gram-positive infections
  • Discontinued Anthrax; Clostridium difficile infections

Most Recent Events

  • 03 Oct 2018 Interim pharmacokinetics data from phase I ORKIDS trial in Gram-positive infections presented at the IDWeek (IDW-2018)
  • 01 Oct 2018 Oritavancin sub-licensed to Menarini group in Europe, Asia-Pacific, China, South Korea, Australia and the Commonwealth of Independent States including Russia
  • 29 Jan 2018 Phase I development in Gram-positive-infections (In adolescents, In children) is ongoing in USA (IV, Infusion) (NCT02134301)
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