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Iodine I 131 derlotuximab biotin

Drug Profile

Iodine I 131 derlotuximab biotin

Alternative Names: 131-I chTNT 1/B; 131-I-chTNT-1/B mAb; Cotara; Iodine-131 radiolabelled TNT monoclonal antibody; Monoclonal antibody TNT-1; TNT-1; Tumour necrosis therapy-1

Latest Information Update: 11 Jan 2018

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At a glance

  • Originator Peregrine Pharmaceuticals
  • Developer Avid Bioservices; MediPharm Biotech
  • Class Antineoplastics; Iodine radioisotopes; Monoclonal antibodies; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Anaplastic astrocytoma; Glioblastoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Lung cancer
  • Phase II Glioblastoma

Most Recent Events

  • 05 Jan 2018 Peregrine Pharmaceuticals is now called Avid Bioservices
  • 12 Aug 2015 Phase-II development for Glioblastoma is ongoing in USA and India; advancement to phase III is dependent upon securing a partner
  • 06 Dec 2012 Peregrine plans a phase III trial for Glioblastoma (recurrent) in USA
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