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AR 623

Drug Profile

AR 623

Alternative Names: All-trans-retinoic acid; ATRA-IV; Atragen; LipoATRA; Tretinoin LF; Tretinoin liposomal

Latest Information Update: 21 Feb 2013

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At a glance

  • Originator Antigenics
  • Developer Agenus; Antigenics
  • Class Antineoplastics; Keratolytics; Retinoids
  • Mechanism of Action Protein synthesis inhibitors; Retinoic acid receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Acute promyelocytic leukaemia; Bladder cancer; Cancer; Kaposi's sarcoma; Non-Hodgkin's lymphoma; Prostate cancer; Renal cancer

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 06 Jan 2011 Antigenics is now called Agenus
  • 04 Oct 2006 Discontinued - Phase-II for Acute myeloid leukaemia in USA (IV)
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