Drug Profile


Alternative Names: DPPE; YMB-1002

Latest Information Update: 11 Mar 2014

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At a glance

  • Originator CancerCare Manitoba; University of Manitoba
  • Developer Shin Poong Pharmaceutical; YM BioSciences
  • Class Antineoplastics; Phenyl ethers; Small molecules
  • Mechanism of Action Estrogen receptor antagonists; Histamine receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Gastric cancer; Prostate cancer

Most Recent Events

  • 02 Feb 2007 YM BioSciences terminates a worldwide pivotal phase III trial (DEC) in advanced Breast cancer
  • 21 Dec 2006 YM Biosciences and TTY Biopharm agree to co-develop tesmilifene for Liver cancer in Taiwan
  • 05 Jun 2006 Phase-II clinical trials in combination with docetaxel in patients with metastatic Breast Cancer in Europe and USA (IV)
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